The primary objective of this study is to enroll an observational cohort of approximately 60 patients with PSP over the course of 24 months using a multicenter study design and to follow each of them for 12 months.
The secondary objective of this study is to develop a robust solution for multi-modal remote monitoring of motor symptoms and function in PSP that can be applied to other Frontotemporal lobar degeneration (FTLD) syndromes.
Clinical diagnosis of possible or probable PSP as defined by the 2017 MDS criteria
Fluent in reading and speaking English and capable of providing informed consent based on the principal investigator's judgement
Able to walk 10 feet unassisted at the time of initial enrollment
Must have a caregiver or study partner who is willing and able to assist with all study-related procedures
Exclusion criteria:
Any neurological, medical, or psychiatric condition that would preclude participation in study activities based on the investigator's judgment.
A history of frequent falls defined as more than 5 falls per month, or who require a walker to ambulate safely at baseline will not be eligible to participate in the study.
A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes
Estimated trial completion date
Dec 30, 2026
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