Status:
Enrolling

Effectiveness of Muscle Energy Techniques and Mulligan Mobilization Along With Conventional Physical Therapy in Knee Joint Osteoarthritis Patients

Phase
Not Specified
Age
≥40
Sponsor
Khyber Medical University Peshawar
Enrollment code
24
Last Updated
May 1, 2025
Locations
3 Countries

Overview

Condition/disease
Osteoarthritis
Modalities
[Not available]
Trial drugs
[not applicable] 
Clinicaltrials.gov ID

Brief summary

This study aims to evaluate the effectiveness of integrating Muscle Energy Technique (MET) and Mulligan Mobilization with conventional physical therapy in the management of knee osteoarthritis (OA), with a specific focus on improving hamstring flexibility and reducing functional limitations. The findings will help inform clinical decision-making and enhance patient outcomes in OA rehabilitation.

Trial locations

Found 3 sites

Bibi Zahida Memorial Hospital, NCS University System

PK - Peshawar

Hayatabad Medical Complex Peshawar

PK - Peshawar

Alkhidmat Hospital Peshawar

PK - Peshawar

Eligibility criteria

Inclusion criteria:

  • Diagnosed cases of osteoarthritis (Grade 1 to 3)
  • X-ray showing Grades I to III on Kellgren Lawrence scale of Osteoarthritis.
  • Residents of Peshawar verified via NADRA CNIC
  • Both genders will be included with unilateral or bilateral knee involvement.
  • Age group 40 and above.
  • Duration of Knee pain for more than 3 months.

Exclusion criteria:

  • History of any previously known neurological conditions i.e. stroke, peripheral neuropathy
  • Fractures in treatment limb.
  • Suspicious of malignancy around the knee joint.
  • Recent under gone surgery
  • Recent Intra-articular injection.
  • Significant comorbid diseases and disabilities are excluded from the study

Study plan

Experimental: Intervention Group

Participants in this group will receive Mulligan Mobilization combined with Conventional Physical Therapy. Mulligan Mobilization includes medial and lateral tibial glides using a Mulligan belt. Each session will consist of 3 sets of 10 repetitions, administered 5 days a week for 3 weeks. In addition, patients will undergo standard conventional physical therapy exercises such as quadriceps strengthening, straight leg raising, and stretching exercises. Each treatment session will last 30 minutes.
Procedure
Mulligan Mobilization
Mulligan Mobilization involves manual tibial glides (medial and lateral) using a mobilization belt. The patient lies supine with the knee flexed between 30°-45°. The therapist applies a sustained glide while the patient actively moves the knee into flexion and extension. The treatment is delivered in 3 sets of 10 repetitions per session, 5 days per week for 3 weeks, along with a conventional physical therapy protocol.

Active Comparator: Control Group

Participants in this group will receive Muscle Energy Technique (MET) targeting the hamstring muscles, in combination with Conventional Physical Therapy. The MET will follow a post-isometric relaxation approach, using both direct and indirect methods depending on patient condition. Each isometric contraction will be held for 10 seconds, followed by a 20-second stretch, repeated for 3 sets. Therapy will be conducted 5 days a week over a 3-week period. Each session will last 30 minutes. The same conventional physical therapy regimen as the intervention group will be applied.
Procedure
Muscle Energy Technique (MET)
Muscle Energy Technique involves the application of post-isometric relaxation targeting hamstring muscles. The therapist applies a 10-second isometric contraction at the resistance barrier, followed by a 20-second passive stretch, progressing into a new range of motion. This technique is applied 3 times per session, 5 days per week for 3 weeks, in combination with a conventional physical therapy protocol.
Allocation: Randomized

Outcome measures

Primary outcome measures

  • Hamstring Flexibility Measured by Goniometer (Baseline (Day 1) and Post-treatment (End of Week 3))
  • Change in Pain Score Using Knee Osteoarthritis Outcome Score-12 questionnaire Questionnaire (Baseline (Day 1) and Post-treatment (End of Week 3))

More information

Official title

Effectiveness of Muscle Energy Techniques and Mulligan Mobilization Along With Conventional Physical Therapy in Knee Joint Osteoarthritis Patients: A Randomized Controlled Trial

Estimated trial completion date

Nov 1, 2025
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